The Accusizer A7000 SIS for USP <788>
particulate matter injections testing
AccuSizer SIS System
The unique technology designed into the A7000 SIS provides capabilities not available in any other liquid particle counter due to each component being the highest specification/performance on the market. The A7000 is not just a liquid particle counter; it is a sophisticated particle size
analyzer as well.
• Measure size and concentration from 0.5 – 400 µm
• Sample conservation after measurement
•1024 size channels defining the complete distribution
• 21 CFR 11 features with security management
Classical light obscuration sensors familiar to pharmaceutical
scientists performing USP <788> testing typically have a lower
particle size limit near 2 μm. The LE400 sensor uses two detectors
(extinction + scattering) to extend the range to 0.5-400 μm.
A 1024 channel pulse height analyzer provides high resolution
results so this is not just a counter – use it as a particle size
analyzer on any of your other samples. The AccuSizer software
allows conversion from number to volume distribution so results
can be compared to other techniques like laser diffraction.
The AccuSizer software is a sophisticated package that
automates USP <788> testing including pass/fail criteria
and acceptance approval.
SPECIFICATIONS
Principle Single particle optical sizing (SPOS) for high resolution particle size and concentration
(particles/mL) analysis. Counts and sizes particles individually, not an ensemble method.
Configurations Includes sensor, counter and syringe sampler system. Syringe volumes of 0.5 – 25 mL, 1024 size channels, conforms to USP <788>.
Sensor LE400-05; 0.5–400 μm when used alone, light extinction and scattering, summation
calibration, particle sensitivity to 10 ppt, concentration limit 10,000 particles/mL, size accuracy
2%, count accuracy 10%, recommended flow rate = 30 mL/min, but can be calibrated at other
flow rates depending on configuration.
Sample 150 μL–25 mL (or larger with multiple syringe pulls). Sample is recovered after the
measurement process.
Options Autosampler
Magnetic stirrer for autosampler
IQ/OQ documentation for user or complete PSS installation
21 CFR Part 11 software
Power 100–120 VAC, 60 Hz or 220–240 VAC, 50 Hz
